What does it mean to become a professional job seeker? You need to know everything there is about the profession(s) you are looking to join and also the job market in general. you should have the answers to basic questions like, What skills are they looking for? Is being a generalist a bad thing? What should I expect to earn as someone coming right out of college?
To get the answers to some of these questions see the College Hiring: Recruiting Trends 2010-2011 an annual publication and this is its 40th edition.